STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
crcBChromosome condensation protein CrcB; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (124 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
    0.819
AHE95696.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.804
AHE95698.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.787
AHE95693.1
Glycosyltransferase family 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
AHE95694.1
3-dehydroquinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the archaeal-type DHQ synthase family.
       0.773
AHE95692.1
Pyrazinamidase/nicotinamidase pxnc; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.726
AHE95699.1
Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.628
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.544
tadA
Adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
      
 0.516
AHE95703.1
Coproporphyrinogen III oxidase; Catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
     
 0.489
Your Current Organism:
Thermocrinis ruber
NCBI taxonomy Id: 75906
Other names: DSM 23557, T. ruber, strain OC 1/4, strain OC 14/7/2
Server load: low (12%) [HD]