Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AHE95985.1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (641 aa)    
Predicted Functional Partners:
AHE96548.1
Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
 
 0.928
argG
Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
   
 0.915
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
   
 
 0.912
AHE95581.1
Aspartate oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.908
AHE96588.1
Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.906
AHE95855.1
Aspartokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family.
  
 
 0.862
AHE95986.1
Glycosyl transferase family 1; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.837
AHE95987.1
Glucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.806
panD
Aspartate decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
  0.800
AHE96801.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
    0.796
Your Current Organism:
Thermocrinis ruber
NCBI taxonomy Id: 75906
Other names: DSM 23557, T. ruber, strain OC 1/4, strain OC 14/7/2
Server load: medium (42%) [HD]