STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAHydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (118 aa)    
Predicted Functional Partners:
AHE96115.1
Hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.993
AHE96113.1
Hydrogenase expression protein HupD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.972
AHE96110.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.950
AHE96112.1
Hydrogenase assembly protein HupF; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.942
AHE96203.1
Mrp; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
   0.919
AHE96106.1
Hydrogenase 2 large subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 0.883
AHE96095.1
Hydrogenase formation protein HypD; Necessary for the synthesis of all three hydrogenase isoenzymes; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.807
AHE96114.1
Ni/Fe hydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.800
AHE96096.1
Hydrogenase maturation protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family.
 
    0.790
AHE96431.1
Flagellar hook assembly protein; Required for flagellar hook formation. May act as a scaffolding protein.
    
   0.633
Your Current Organism:
Thermocrinis ruber
NCBI taxonomy Id: 75906
Other names: DSM 23557, T. ruber, strain OC 1/4, strain OC 14/7/2
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