Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AHE96280.1Nitrogen-fixing protein NifU; Derived by automated computational analysis using gene prediction method: Protein Homology. (83 aa)    
Predicted Functional Partners:
AHE96276.1
FeS cluster assembly scaffold IscU; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.910
AHE96277.1
Thiamine biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.823
AHE96278.1
SirA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
       0.818
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.806
AHE96279.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
lipA
Radical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
   
 0.623
AHE96293.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family.
  
 
 0.590
AHE96275.1
leucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
       0.576
AHE95667.1
Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
   
   0.550
AHE95995.1
Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.550
Your Current Organism:
Thermocrinis ruber
NCBI taxonomy Id: 75906
Other names: DSM 23557, T. ruber, strain OC 1/4, strain OC 14/7/2
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.