STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
oggDNA lyase; Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 7-oxoG) from DNA. Also nicks DNA at apurinic/apyrimidinic sites (AP sites); Belongs to the type-2 OGG1 family. (224 aa)    
Predicted Functional Partners:
AHE96352.1
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
       0.773
AHE96359.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.648
AHE96347.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.560
AHE96351.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.556
rgy
Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family.
  
     0.556
AHE96407.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.525
AHE95644.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.477
murG
UDP-diphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
       0.469
AHE96344.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.469
AHE96345.1
Biopolymer transporter ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.469
Your Current Organism:
Thermocrinis ruber
NCBI taxonomy Id: 75906
Other names: DSM 23557, T. ruber, strain OC 1/4, strain OC 14/7/2
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