| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHE95703.1 | AHE96658.1 | THERU_02340 | THERU_08125 | Coproporphyrinogen III oxidase; Catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | 0.917 |
| AHE95703.1 | hemC | THERU_02340 | THERU_02295 | Coproporphyrinogen III oxidase; Catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.547 |
| AHE95703.1 | hemE | THERU_02340 | THERU_08070 | Coproporphyrinogen III oxidase; Catalyzes the oxygen-independent formation of protoporphyrinogen-IX from coproporphyrinogen-III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.935 |
| AHE96074.1 | AHE96075.1 | THERU_04675 | THERU_04680 | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.981 |
| AHE96074.1 | AHE96127.1 | THERU_04675 | THERU_04975 | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
| AHE96074.1 | AHE96780.1 | THERU_04675 | THERU_03200 | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.900 |
| AHE96074.1 | hemC | THERU_04675 | THERU_02295 | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.980 |
| AHE96074.1 | hemE | THERU_04675 | THERU_08070 | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.926 |
| AHE96075.1 | AHE96074.1 | THERU_04680 | THERU_04675 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.981 |
| AHE96075.1 | AHE96127.1 | THERU_04680 | THERU_04975 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| AHE96075.1 | AHE96780.1 | THERU_04680 | THERU_03200 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.908 |
| AHE96075.1 | hemC | THERU_04680 | THERU_02295 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.962 |
| AHE96075.1 | hemE | THERU_04680 | THERU_08070 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.917 |
| AHE96127.1 | AHE96074.1 | THERU_04975 | THERU_04675 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
| AHE96127.1 | AHE96075.1 | THERU_04975 | THERU_04680 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| AHE96127.1 | AHE96780.1 | THERU_04975 | THERU_03200 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. | 0.908 |
| AHE96127.1 | hemC | THERU_04975 | THERU_02295 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.962 |
| AHE96127.1 | hemE | THERU_04975 | THERU_08070 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.917 |
| AHE96645.1 | hemE | THERU_08055 | THERU_08070 | Geranylgeranyl reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.785 |
| AHE96645.1 | trm1 | THERU_08055 | THERU_08065 | Geranylgeranyl reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | N2,N2-dimethylguanosine tRNA methyltransferase; Dimethylates the guanine residues at position 26 and 27 of one or more tRNAs using S-adenosyl-L-methionine as donor of the methyl groups; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. | 0.804 |
