| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AHE96074.1 | AHE96075.1 | THERU_04675 | THERU_04680 | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.981 |
| AHE96074.1 | AHE96127.1 | THERU_04675 | THERU_04975 | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
| AHE96074.1 | AHE96659.1 | THERU_04675 | THERU_08130 | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.578 |
| AHE96074.1 | hemC | THERU_04675 | THERU_02295 | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.980 |
| AHE96075.1 | AHE96074.1 | THERU_04680 | THERU_04675 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.981 |
| AHE96075.1 | AHE96127.1 | THERU_04680 | THERU_04975 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| AHE96075.1 | AHE96659.1 | THERU_04680 | THERU_08130 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
| AHE96075.1 | AHE96755.1 | THERU_04680 | THERU_01640 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.769 |
| AHE96075.1 | hemC | THERU_04680 | THERU_02295 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.962 |
| AHE96127.1 | AHE96074.1 | THERU_04975 | THERU_04675 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
| AHE96127.1 | AHE96075.1 | THERU_04975 | THERU_04680 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.901 |
| AHE96127.1 | AHE96659.1 | THERU_04975 | THERU_08130 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
| AHE96127.1 | AHE96755.1 | THERU_04975 | THERU_01640 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.769 |
| AHE96127.1 | hemC | THERU_04975 | THERU_02295 | uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: Protein Homology. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.963 |
| AHE96658.1 | AHE96659.1 | THERU_08125 | THERU_08130 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.786 |
| AHE96658.1 | AHE96660.1 | THERU_08125 | THERU_08135 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.773 |
| AHE96658.1 | AHE96661.1 | THERU_08125 | THERU_08140 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.773 |
| AHE96658.1 | hemC | THERU_08125 | THERU_02295 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.456 |
| AHE96658.1 | thiG | THERU_08125 | THERU_08120 | Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. | Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.776 |
| AHE96659.1 | AHE96074.1 | THERU_08130 | THERU_04675 | Siroheme synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Uroporphyrinogen III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.578 |