STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A0K0EY51Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (211 aa)    
Predicted Functional Partners:
A0A0K0F1C2
Peripheral plasma membrane protein CASK (inferred by orthology to a D. melanogaster protein); Belongs to the MAGUK family.
    
 0.998
A0A0K0F1C4
Peripheral plasma membrane protein CASK (inferred by orthology to a D. melanogaster protein).
    
 0.997
A0A0K0EZQ1
Adenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...]
    
 0.969
A0A0K0FUL9
Uncharacterized protein.
    
 0.921
A0A0K0FN99
MAGUK p55 subfamily member 5 (inferred by orthology to a human protein); Belongs to the MAGUK family.
    
 0.841
A0A0K0EXQ4
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.822
A0A0K0EXQ5
CaMKII_AD domain-containing protein.
    
 0.822
A0A0K0EVY9
Rim (inferred by orthology to a D. melanogaster protein).
    
 0.799
A0A0K0FLY8
GH24511p (inferred by orthology to a D. melanogaster protein); Belongs to the ubiquitin-activating E1 family.
   
 0.733
A0A0K0F496
Receptor protein-tyrosine kinase.
    
 
 0.721
Your Current Organism:
Strongyloides venezuelensis
NCBI taxonomy Id: 75913
Other names: S. venezuelensis
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.