STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
katGCatalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (745 aa)    
Predicted Functional Partners:
ORB68878.1
Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
    
 0.979
ORB64606.1
Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.915
ORB67849.1
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
     
 0.904
hisC
Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.871
ORB67154.1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.871
ORB66227.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.865
pat
tRNA-Ser; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
     
 0.865
ORB66329.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
  
 0.834
rpoB
Alpha/beta hydrolase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.819
gyrB
DNA topoisomerase (ATP-hydrolyzing) subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP [...]
      
 0.819
Your Current Organism:
Mycolicibacterium tusciae
NCBI taxonomy Id: 75922
Other names: CCUG 50996, CIP 106367, DSM 44338, JCM 12692, M. tusciae, Mycobacterium sp. FI-25796, Mycobacterium tusciae, strain FI-25796
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