STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORB67750.1Ammonia channel protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)    
Predicted Functional Partners:
ORB65022.1
Transcriptional regulator; Indirectly regulates nitrogen metabolism; at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA); at low nitrogen levels P-II is uridylylated to form PII-UMP and interacts with an adenylyltransferase (GlnE) that activates GlnA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
ORB67151.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.675
ORB62950.1
Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.649
ORB66325.1
Glutamate synthase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.647
ORB63952.1
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.582
ORB62270.1
Stage II sporulation protein E; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.582
ORB64658.1
Anti-sigma regulatory factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.507
glnD
[protein-PII] uridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism.
 
   
 0.505
ORB66252.1
Type I glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.494
ORB63139.1
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
  
  
 0.482
Your Current Organism:
Mycolicibacterium tusciae
NCBI taxonomy Id: 75922
Other names: CCUG 50996, CIP 106367, DSM 44338, JCM 12692, M. tusciae, Mycobacterium sp. FI-25796, Mycobacterium tusciae, strain FI-25796
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