STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORB66134.1Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. (140 aa)    
Predicted Functional Partners:
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.963
ORB66135.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.953
rpoB
Alpha/beta hydrolase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.931
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.929
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.927
sigA
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
  
 
 0.906
ORB68862.1
RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
 
 0.906
ORB68878.1
Transcriptional repressor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
  
   
 0.860
ORB68436.1
ArsR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.824
ORB68863.1
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.824
Your Current Organism:
Mycolicibacterium tusciae
NCBI taxonomy Id: 75922
Other names: CCUG 50996, CIP 106367, DSM 44338, JCM 12692, M. tusciae, Mycobacterium sp. FI-25796, Mycobacterium tusciae, strain FI-25796
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