STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ORB65037.1Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)    
Predicted Functional Partners:
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
 
 0.745
ORB68488.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.638
ORB67630.1
Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.621
ORB68426.1
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.594
ORB65040.1
Dihydroxyacetone kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.543
ORB65038.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.536
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
       0.536
ORB64033.1
Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.501
ORB62383.1
Deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.496
ORB68754.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.411
Your Current Organism:
Mycolicibacterium tusciae
NCBI taxonomy Id: 75922
Other names: CCUG 50996, CIP 106367, DSM 44338, JCM 12692, M. tusciae, Mycobacterium sp. FI-25796, Mycobacterium tusciae, strain FI-25796
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.