Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ORB63496.13-ketosteroid-delta-1-dehydrogenase; Initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)    
Predicted Functional Partners:
ORB63391.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.968
ORB61226.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.966
ORB63902.1
NADP oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.958
ORB66059.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.951
ORB63382.1
3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.946
ORB63908.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.939
ORB66979.1
Succinate dehydrogenase, cytochrome b556 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.931
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.923
ORB64283.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.907
ORB66976.1
Succinate dehydrogenase iron-sulfur subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.895
Your Current Organism:
Mycolicibacterium tusciae
NCBI taxonomy Id: 75922
Other names: CCUG 50996, CIP 106367, DSM 44338, JCM 12692, M. tusciae, Mycobacterium sp. FI-25796, Mycobacterium tusciae, strain FI-25796
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