STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
menGBifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (228 aa)    
Predicted Functional Partners:
menA
1,4-dihydroxy-2-naphthoate polyprenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily.
    
 0.900
ORB67650.1
Ubiquinone biosynthesis methyltransferase UbiE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.882
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
     
 0.826
ORB62565.1
Short-chain dehydrogenase/reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.774
ORB67810.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.684
ORB64726.1
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.681
ORB67817.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.659
ORB65758.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.659
ORB61082.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.659
ORB60313.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.659
Your Current Organism:
Mycolicibacterium tusciae
NCBI taxonomy Id: 75922
Other names: CCUG 50996, CIP 106367, DSM 44338, JCM 12692, M. tusciae, Mycobacterium sp. FI-25796, Mycobacterium tusciae, strain FI-25796
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