node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ORB61256.1 | ORB63144.1 | BST47_28480 | BST47_20700 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.815 |
ORB61256.1 | ORB63908.1 | BST47_28480 | BST47_17905 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.692 |
ORB61256.1 | ORB68648.1 | BST47_28480 | BST47_01705 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | rRNA cytosine-C5-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. | 0.737 |
ORB61256.1 | fmt | BST47_28480 | BST47_01710 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.822 |
ORB61256.1 | gcvT | BST47_28480 | BST47_10400 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.759 |
ORB61256.1 | glyA | BST47_28480 | BST47_17270 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.937 |
ORB61256.1 | purA | BST47_28480 | BST47_04830 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.676 |
ORB61256.1 | purH | BST47_28480 | BST47_16335 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.865 |
ORB61256.1 | purN | BST47_28480 | BST47_16330 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.861 |
ORB61256.1 | thyA | BST47_28480 | BST47_20995 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.708 |
ORB63144.1 | ORB61256.1 | BST47_20700 | BST47_28480 | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.815 |
ORB63144.1 | ORB63908.1 | BST47_20700 | BST47_17905 | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.516 |
ORB63144.1 | fmt | BST47_20700 | BST47_01710 | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.680 |
ORB63144.1 | gcvT | BST47_20700 | BST47_10400 | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. | 0.923 |
ORB63144.1 | glyA | BST47_20700 | BST47_17270 | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.948 |
ORB63144.1 | purH | BST47_20700 | BST47_16335 | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.769 |
ORB63144.1 | purN | BST47_20700 | BST47_16330 | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.731 |
ORB63144.1 | thyA | BST47_20700 | BST47_20995 | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.567 |
ORB63908.1 | ORB61256.1 | BST47_17905 | BST47_28480 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.692 |
ORB63908.1 | ORB63144.1 | BST47_17905 | BST47_20700 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.516 |