Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iolC_1Ketodeoxygluconokinase; Catalyzes the formation of 2-dehydro-3-deoxy-D-gluconate-6-phosphate from 2-dehydro-3-deoxy-D-gluconate; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)    
Predicted Functional Partners:
eda_1
2-dehydro-3-deoxyphosphogluconate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.996
uxuA_2
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.991
rpe
Ribulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.980
fruA_4
PTS system fructose-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.869
AKA10261.1
Converts D-mannonate to D-mannuronate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 0.789
AKA10262.1
L-dehydroascorbate transporter large permease subunit; TRAP family transporter; with YiaMO is involved in the uptake of L-dehydroascorbate; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.642
AKA10263.1
C4-dicarboxylate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.623
AKA10264.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.552
AKA10265.1
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.549
iolC_1-2
Fructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.
  
  
 
0.531
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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