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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gntR_1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)    
Predicted Functional Partners:
ccpA
PurR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.774
fruR
Sucrose operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.774
fruB
PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.531
secE
Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
       0.510
nusG
Transcription antiterminator NusG; Participates in transcription elongation, termination and antitermination.
       0.510
ulaB_2
PTS mannitol transporter subunit IIB; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.470
rplA_1
50S ribosomal protein L1; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the universal ribosomal protein uL1 family.
   
   0.450
fruA_4
PTS system fructose-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.430
ptsH
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.424
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
   0.407
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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