Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKA10391.1Polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)    
Predicted Functional Partners:
wecF
4-alpha-L-fucosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     0.984
rffM
UDP-N-acetyl-D-mannosaminuronic acid transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyltransferase 26 family.
 
  
 0.898
wzzE_1
Lipopolysaccharide chain length determinant protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.832
AKA10388.1
Histone acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.797
wzzE_2
Wzz; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.795
mukF
Condesin subunit F; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity.
  
   
 0.787
mukE
Condesin subunit E; Acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.787
holD
DNA polymerase III subunit psi; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
  
   
 0.770
ycdY
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.766
mukB
Cell division protein MukB; SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.759
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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