| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKA10681.1 | sspB | WC39_02925 | WC39_07305 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.736 |
| AKA10681.1 | tatA | WC39_02925 | WC39_01960 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.563 |
| guaA | murI | WC39_06545 | WC39_00440 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.494 |
| guaA | secY | WC39_06545 | WC39_12995 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.552 |
| guaA | tatA | WC39_06545 | WC39_01960 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Preprotein translocase subunit SecA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.922 |
| guaA | tatB | WC39_06545 | WC39_01965 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Preprotein translocase subunit TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.922 |
| hemB | tatA | WC39_01975 | WC39_01960 | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | Preprotein translocase subunit SecA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.640 |
| hemB | tatB | WC39_01975 | WC39_01965 | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | Preprotein translocase subunit TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.635 |
| hemB | tatC | WC39_01975 | WC39_01970 | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | Twin-arginine protein translocation system subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.621 |
| hemB | ubiB | WC39_01975 | WC39_01955 | Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. | Ubiquinone biosynthesis protein UbiB; An Escherichia coli mutant results in accumulation of octaprenylphenol and no ubiquinone; functions in the formation of 2-octaprenyl-6-hydroxy-phenol from 2-octaprenylphenol in ubiquinone (coenzyme Q) biosynthesis; similar to eukaryotic proteins that exhibit kinase functions; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.636 |
| murI | guaA | WC39_00440 | WC39_06545 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.494 |
| murI | secD | WC39_00440 | WC39_10070 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Preprotein translocase subunit SecD; Part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.460 |
| murI | secY | WC39_00440 | WC39_12995 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.496 |
| murI | tatA | WC39_00440 | WC39_01960 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Preprotein translocase subunit SecA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.554 |
| murI | tatB | WC39_00440 | WC39_01965 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Preprotein translocase subunit TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.550 |
| secD | murI | WC39_10070 | WC39_00440 | Preprotein translocase subunit SecD; Part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.460 |
| secD | secY | WC39_10070 | WC39_12995 | Preprotein translocase subunit SecD; Part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.928 |
| secD | tatA | WC39_10070 | WC39_01960 | Preprotein translocase subunit SecD; Part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit SecA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.609 |
| secD | tatB | WC39_10070 | WC39_01965 | Preprotein translocase subunit SecD; Part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | Preprotein translocase subunit TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.645 |
| secD | tatC | WC39_10070 | WC39_01970 | Preprotein translocase subunit SecD; Part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; Derived by automated computational analysis using gene prediction method: Protein Homology. | Twin-arginine protein translocation system subunit TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.470 |
