Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
manZ_1PTS N-acetylgalactosamine transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)    
Predicted Functional Partners:
manY_2
PTS mannose transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
manX
PTS mannose transporter subunit IIAB; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIA transfers a phosphoryl group to subunit IIB; subunit IIB transfers the phosphoryl group to the substrate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
agaC
PTS sorbose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.995
manX_5
PTS beta-glucoside transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.956
levE_1
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.937
fruA_4
PTS system fructose-specific transporter subunits IIBC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.819
yobD
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.731
lacE_1
PTS fructose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.608
licR
Transcription antiterminator BglG; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.558
fruB
PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.483
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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