STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
manXPTS mannose transporter subunit IIAB; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; subunit IIA transfers a phosphoryl group to subunit IIB; subunit IIB transfers the phosphoryl group to the substrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)    
Predicted Functional Partners:
manZ_1
PTS N-acetylgalactosamine transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
manY_2
PTS mannose transporter subunit IIC; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
agaC
PTS sorbose transporter subunit IIC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
manZ_2
PTS mannose transporter subunit IID; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
fruB
PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.999
ptsH
PTS sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.999
manX_5
PTS beta-glucoside transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
0.971
AKA10239.1
alpha-D-phosphohexomutase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.913
iolC_1-2
Fructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family.
    
 0.827
yobD
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.754
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.