Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
xerC_2Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (267 aa)    
Predicted Functional Partners:
AKA11605.1
Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.725
xerD_3
Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.695
AKA10533.1
Restriction endonuclease subunit S; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.646
ftsK
Cell division protein FtsK; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.494
AKA10535.1
Restriction endonuclease subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.479
xerC
Site-specific tyrosine recombinase which cuts and rejoins DNA molecules; binds cooperatively to specific DNA consensus sites; forms a heterotetrameric complex with XerC; XerCD exhibit similar sequences; essential to convert chromosome dimers to monomers during cell division and functions during plasmid segregation; cell division protein FtsK may regulate the XerCD complex; enzyme from Streptococcus group has unusual active site motifs; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
0.477
recR
Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.
  
   
 0.439
sppA_3
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.434
hsdR_1
Restriction endonuclease EcoEI subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.425
nusG
Transcription antiterminator NusG; Participates in transcription elongation, termination and antitermination.
      
 0.417
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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