| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AKA10629.1 | matP | WC39_02650 | WC39_01030 | Hypothetical protein; The crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0149 family. | Ter macrodomain organizer matS-binding protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. | 0.583 |
| AKA10629.1 | zapA | WC39_02650 | WC39_02655 | Hypothetical protein; The crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0149 family. | Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.744 |
| AKA11006.1 | ftsL | WC39_04710 | WC39_02575 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.756 |
| AKA11006.1 | matP | WC39_04710 | WC39_01030 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ter macrodomain organizer matS-binding protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. | 0.763 |
| AKA11006.1 | mukB | WC39_04710 | WC39_06490 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein MukB; SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.765 |
| AKA11006.1 | mukE | WC39_04710 | WC39_06485 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Condesin subunit E; Acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.765 |
| AKA11006.1 | mukF | WC39_04710 | WC39_06480 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Condesin subunit F; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. | 0.768 |
| AKA11006.1 | uspA | WC39_04710 | WC39_06460 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Universal stress protein A; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family. | 0.720 |
| AKA11006.1 | zapA | WC39_04710 | WC39_02655 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.691 |
| AKA11006.1 | zapB | WC39_04710 | WC39_07190 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.756 |
| ftsL | AKA11006.1 | WC39_02575 | WC39_04710 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.756 |
| ftsL | matP | WC39_02575 | WC39_01030 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Ter macrodomain organizer matS-binding protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. | 0.731 |
| ftsL | mukB | WC39_02575 | WC39_06490 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Cell division protein MukB; SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.728 |
| ftsL | mukE | WC39_02575 | WC39_06485 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Condesin subunit E; Acts with MukB and MukF to condense the chromosome and allow for segregation during cell division; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.761 |
| ftsL | mukF | WC39_02575 | WC39_06480 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Condesin subunit F; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. | 0.761 |
| ftsL | uspA | WC39_02575 | WC39_06460 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Universal stress protein A; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family. | 0.633 |
| ftsL | zapA | WC39_02575 | WC39_02655 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.805 |
| ftsL | zapB | WC39_02575 | WC39_07190 | Cell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Cell division protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. | 0.759 |
| ihfA | zapA | WC39_06610 | WC39_02655 | Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | Cell division protein ZapA; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. | 0.724 |
| matP | AKA10629.1 | WC39_01030 | WC39_02650 | Ter macrodomain organizer matS-binding protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. | Hypothetical protein; The crystal structure of Haemophilus influenzae HI0817 showed that this protein forms dimers; function unknown; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0149 family. | 0.583 |
