Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKA10701.1Epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)    
Predicted Functional Partners:
raiA
Ribosome-associated inhibitor A; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.730
argR_2
Arginine repressor; Regulates arginine biosynthesis genes.
       0.714
uvrD
DNA-dependent helicase II; Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.628
AKA12235.1
Dihydroorotate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.497
parC_2
DNA topoisomerase IV subunit A; Decatenates newly replicated chromosomal DNA and relaxes positive and negative DNA supercoiling; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.492
mdh_2
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
       0.467
lolB_2
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.446
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
  
    0.433
lepB
Signal peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
   
    0.417
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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