Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lptB_2Sugar ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)    
Predicted Functional Partners:
lptF
Lipopolysaccharide ABC transporter permease; With LptBGC is involved in lipopolysaccharide export; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
lptG_1
With LptABCF is involved in the transport of lipopolysaccharides; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
lptC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.995
lptA
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.982
ptsN
PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.774
lpxA
UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
  
 0.772
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
  
 0.738
kpsF
Arabinose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.725
yhbJ_1
glmZ(sRNA)-inactivating NTPase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RapZ-like family.
  
    0.691
lpxC
UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
  
 0.666
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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