Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
msrAB_2Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (168 aa)    
Predicted Functional Partners:
msrB
Methionine sulfoxide reductase B; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.993
dsbD_2
Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.707
AKA12355.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.627
metH_3
Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.598
AKA10255.1
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.573
grxA
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.563
macB_3
Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
     
 0.557
dsbE_3
Dihydroneopterin aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.516
dsbE_1
Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.516
psuT_4
Nucleoside transporter NupC; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.506
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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