| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hflB | hflC_1 | WC39_07795 | WC39_04400 | Inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. | Protein HflC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.854 |
| hflB | hflK | WC39_07795 | WC39_04395 | Inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. | Membrane protease HflK; HflC and HflK could encode or regulate a protease. | 0.934 |
| hflB | hflX_1 | WC39_07795 | WC39_01775 | Inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. | GTPase HflX; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. | 0.400 |
| hflB | miaA | WC39_07795 | WC39_01785 | Inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.407 |
| hflB | yidC | WC39_07795 | WC39_01010 | Inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. | Membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.435 |
| hflC_1 | hflB | WC39_04400 | WC39_07795 | Protein HflC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. | 0.854 |
| hflC_1 | hflK | WC39_04400 | WC39_04395 | Protein HflC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protease HflK; HflC and HflK could encode or regulate a protease. | 0.996 |
| hflC_1 | hflX_1 | WC39_04400 | WC39_01775 | Protein HflC; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTPase HflX; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. | 0.421 |
| hflC_1 | miaA | WC39_04400 | WC39_01785 | Protein HflC; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.434 |
| hflC_1 | purA_2 | WC39_04400 | WC39_04405 | Protein HflC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.518 |
| hflC_1 | trxA | WC39_04400 | WC39_04390 | Protein HflC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. | 0.461 |
| hflC_1 | yidC | WC39_04400 | WC39_01010 | Protein HflC; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.434 |
| hflK | hflB | WC39_04395 | WC39_07795 | Membrane protease HflK; HflC and HflK could encode or regulate a protease. | Inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. | 0.934 |
| hflK | hflC_1 | WC39_04395 | WC39_04400 | Membrane protease HflK; HflC and HflK could encode or regulate a protease. | Protein HflC; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.996 |
| hflK | hflX_1 | WC39_04395 | WC39_01775 | Membrane protease HflK; HflC and HflK could encode or regulate a protease. | GTPase HflX; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. | 0.721 |
| hflK | miaA | WC39_04395 | WC39_01785 | Membrane protease HflK; HflC and HflK could encode or regulate a protease. | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.493 |
| hflK | purA_2 | WC39_04395 | WC39_04405 | Membrane protease HflK; HflC and HflK could encode or regulate a protease. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.541 |
| hflK | trxA | WC39_04395 | WC39_04390 | Membrane protease HflK; HflC and HflK could encode or regulate a protease. | Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. | 0.473 |
| hflK | yidC | WC39_04395 | WC39_01010 | Membrane protease HflK; HflC and HflK could encode or regulate a protease. | Membrane protein insertase; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.573 |
| hflX_1 | hflB | WC39_01775 | WC39_07795 | GTPase HflX; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. | Inner membrane metalloprotease; may be involved in degradation of aberrant cytoplasmic and membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AAA ATPase family. | 0.400 |
STRING v12.5 is now available!
