Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
bolABolA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (103 aa)    
Predicted Functional Partners:
grxD
Glutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 0.864
AKA11006.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.637
nfuA
Amino acid ABC transporter substrate-binding protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins.
  
 
 0.543
AKA10492.1
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family.
   
  
 0.482
AKA10436.1
S-formylglutathione hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.432
purL_1
Phosphoribosylformylglycinamidine synthase; Catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.426
xthA
Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.423
AKA12355.1
Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.404
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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