lolA protein (Mannheimia haemolytica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Mannheimia haemolytica

NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AKA11026.1	amiB	WC39_04815	WC39_04230	Peptidoglycan-associated outer membrane lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.	N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.496
AKA11026.1	lolA	WC39_04815	WC39_05615	Peptidoglycan-associated outer membrane lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.695
AKA11026.1	lolB_2	WC39_04815	WC39_07865	Peptidoglycan-associated outer membrane lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.650
AKA11026.1	lolC	WC39_04815	WC39_03135	Peptidoglycan-associated outer membrane lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.827
AKA11026.1	lolE_3	WC39_04815	WC39_03145	Peptidoglycan-associated outer membrane lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Outer membrane-specific lipoprotein transporter subunit LolE; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.810
AKA11026.1	lptD_3	WC39_04815	WC39_04960	Peptidoglycan-associated outer membrane lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.	LPS biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.470
AKA11026.1	ompA_2	WC39_04815	WC39_06090	Peptidoglycan-associated outer membrane lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Plastocyanin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.649
AKA11026.1	yaeT_2	WC39_04815	WC39_08700	Peptidoglycan-associated outer membrane lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Part of a complex with YfgL, YfiO, and NlpB involved in outer membrane protein biosynthesis; involved in the assembly of outer membrane proteins; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.894
amiB	AKA11026.1	WC39_04230	WC39_04815	N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidoglycan-associated outer membrane lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.496
amiB	lolA	WC39_04230	WC39_05615	N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.729
amiB	macB_3	WC39_04230	WC39_06885	N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.525
amiB	ompA_2	WC39_04230	WC39_06090	N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Plastocyanin; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.413
lolA	AKA11026.1	WC39_05615	WC39_04815	Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Peptidoglycan-associated outer membrane lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.695
lolA	amiB	WC39_05615	WC39_04230	Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.729
lolA	lolB_2	WC39_05615	WC39_07865	Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.958
lolA	lolC	WC39_05615	WC39_03135	Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.881
lolA	lolD	WC39_05615	WC39_03140	Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	ABC transporter ATP-binding protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	0.915
lolA	lolE_3	WC39_05615	WC39_03145	Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Outer membrane-specific lipoprotein transporter subunit LolE; Part of the ATP-dependent transport system LolCDE; responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.858
lolA	lptD_3	WC39_05615	WC39_04960	Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	LPS biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.774
lolA	macB_3	WC39_05615	WC39_06885	Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Macrolide transporter; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.	0.740

page 1 of 5

Server load: low (14%) [HD]

Share

Network

Neighborhood

Experiments

Co-occurrence

Databases

Co-expression

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About