STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceEE1 component; part of pyruvate dehydrogenase; forms a complex with DlaT and LpdC; Derived by automated computational analysis using gene prediction method: Protein Homology. (885 aa)    
Predicted Functional Partners:
aceF
E2 component of pyruvate dehydrogenase multienzyme complex; in Escherichia coli AceF contains three N-terminal lipoyl domains; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.997
lpdA_2
E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.984
AKA12243.1
Oxaloacetate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.930
maeB
NADH-ubiquinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.919
pykA_2
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.918
lldD
Lactate dehydrogenase; Flavin mononucleotide-dependent dehydrogenase; functions in aerobic respiration and also has a role in anaerobic nitrate respiration; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.910
ilvM
Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.905
pflB_1
Pyruvate formate-lyase; Formate acetyltransferase; catalyzes the formation of formate and acetyl-CoA from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.902
dld_2
Component of the membrane-bound D-lactate oxidase, FAD-binding, NADH independent; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.901
aldA
Aldehyde dehydrogenase; NAD-linked; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
     
 0.901
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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