Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mreDRod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. (162 aa)    
Predicted Functional Partners:
AKA11693.1
Rod shape-determining protein MreC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.988
mreB_1
Rod shape-determining protein MreB; Functions in MreBCD complex in some organisms; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.836
rarA_2
Recombination factor protein RarA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
rodZ
DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.713
ftsQ
Cell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly.
  
  
 0.692
ftsB
Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic.
  
   
 0.683
penA
Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
  
 0.619
zipA
Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins.
  
   
 0.601
mrdB
Cell wall shape-determining protein; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
  
  
 0.597
yceD
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.554
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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