STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKA11704.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1125 aa)    
Predicted Functional Partners:
aroC_2
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
       0.792
menE_3
O-succinylbenzoic acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.791
seqA_1
Negative modulator of initiation of replication; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.767
mepA
D-alanyl-D-alanine endopeptidase; functions in hydrolyzing cell wall peptidoglycan; similar to LAS metallopeptidases; forms a dimer in periplasm; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.720
nrfG_1
Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.561
ybfF
acyl-CoA esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.531
cmoA_1
tRNA methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM).
       0.530
topB_2
DNA topoisomerase III; Decatenates replicating daughter chromosomes; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.529
AKA11078.1
Tubulin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.485
uspA
Universal stress protein A; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
  
     0.476
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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