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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
proB_4Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (322 aa)    
Predicted Functional Partners:
proA_1
Gamma-glutamyl phosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
putA
Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
    
 0.940
rocD
Ornithine--oxo-acid aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde.
   
 0.913
proB_3
Gamma-glutamyl kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.901
nth
Endonuclease III; DNA-(apurinic or apyrimidinic site) lyase; has apurinic or apyrimidinic endonuclease activity and DNA N-glycosylase activity; removed damaged DNA at cytosines, thymines and guanines; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.776
AKA11768.1
Gamma-glutamyl kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
yfcA_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
folA
Dihydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.745
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
 
 
 0.704
thrA
Aspartate kinase; Multifunctional homotetrameric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.501
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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