Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dsbA_2Thiol:disulfide interchange protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)    
Predicted Functional Partners:
dsbB
Dihydrolipoamide acyltransferase; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
 
 
 0.935
dsbC_1
Protein-disulfide isomerase; DsbC; periplasmic protein with protein disulfide isomerase activity; this protein also shows disulfide oxidoreductase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.723
AKA11839.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.700
AKA10681.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.682
ypjD
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.643
lolA
Lipoprotein chaperone; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
  
   
 0.630
yihD_2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.616
holA
DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.586
lptD_3
LPS biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.581
lptE
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.572
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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