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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
umuDTranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)    
Predicted Functional Partners:
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.863
dinB_2
DNA polymerase IV; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DNA polymerase type-Y family.
  
 
 0.634
AKA11912.1
Heptosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.574
AKA11545.1
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S24 family.
  
     0.525
recN_2
Recombination and repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.512
AKA11903.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0319 family.
  
     0.486
AKA10695.1
Hemolysin regulation protein AhpA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.462
grcA
Autonomous glycyl radical cofactor GrcA; Acts as a radical domain for damaged PFL and possibly other radical proteins.
       0.459
AKA12585.1
Phospholipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.456
holC
DNA polymerase III subunit chi; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.455
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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