Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fhuEFerric alcaligin siderophore receptor; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)    
Predicted Functional Partners:
pupA
TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.919
fhuD
Iron ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.726
fhuC_2
ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.720
fhuB_2
Ferrichrome transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
     
 0.687
fhuB_1
Ferrichrome transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
     
 0.687
fes
Short-chain isoprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.561
tonB
Energy transducer TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (By similarity); Belongs to the TonB family.
  
 
 0.550
AKA11405.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.499
AKA12264.1
Ligand-gated channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.457
fhuA_2
GlcNAc transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.454
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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