Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AKA12355.1Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)    
Predicted Functional Partners:
gor_3
Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.989
gst
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GST superfamily.
  
 0.981
gstB
Gst protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.981
AKA11034.1
Glutathione S-transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.978
lysX
Ribosomal protein S6 modification protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RimK family.
    
 0.779
lpdA_2
E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.710
nrdA_3
Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the rate-limiting step in dNTP synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.691
nrdE
Ribonucleotide-diphosphate reductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.691
trxB_2
Thioredoxin reductase; Catalyzes the transfer of electrons from NADPH to thioredoxin; FAD/NAD(P) binding; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.641
msrAB_2
Methionine sulfoxide reductase A; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
 
 0.627
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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