STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rocDOrnithine--oxo-acid aminotransferase; Catalyzes the interconversion of ornithine to glutamate semialdehyde. (396 aa)    
Predicted Functional Partners:
putA
Proline dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
    
 0.943
proB_4
Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
   
 0.913
proB_3
Gamma-glutamyl kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.913
argA
N-acetylglutamate synthase; Catalyzes the formation of N-acetyl-L-glutamate from L-glutamate and acetyl-CoA in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. ArgA subfamily.
  
  
 0.838
arcB_1
Catalyzes the formation of ornithine and carbamylphosphate from citrulline in the arginine catabolic pathway; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.785
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the reduction of N-acetyl-5-glutamyl phosphate to N-acetyl-L-glutamate 5-semialdehyde in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.773
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
  
 0.753
argG_2
Argininosuccinate synthase; Catalyzes the formation of arginosuccinate from citrulline and aspartate in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.745
argH_1
Argininosuccinate lyase; Catalyzes the formation of arginine from (N-L-arginino)succinate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.734
argR_2
Arginine repressor; Regulates arginine biosynthesis genes.
  
  
 0.498
Your Current Organism:
Mannheimia haemolytica
NCBI taxonomy Id: 75985
Other names: ATCC 33396, CCUG 12392, CCUG 408, CIP 103426, DSM 10531, M. haemolytica, NCTC 9380, Pasteurella haemolytica, strain J.A. Watt 1266AB
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