STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SKA87759.1DivIVA domain-containing protein; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation. (97 aa)    
Predicted Functional Partners:
ponA
Penicillin-binding protein 1A.
 
 
 
 0.872
ezrA
Septation ring formation regulator; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
 
 0.851
SKA92175.1
Penicillin-binding protein.
   
 
 0.814
SKA97357.1
Penicillin-binding protein, 1A family.
   
 
 0.814
pbp2A2
Penicillin-binding protein 2A.
   
 
 0.814
dacB-2
Penicillin-binding protein 1A.
   
 
 0.814
SKB00483.1
Uncharacterized protein.
 
   
 0.791
SKB00231.1
Serine/threonine protein kinase.
 
 
 0.773
divIB
Cell division protein FtsQ; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
 
   
 0.769
pbp2A
Cell division protein FtsI/penicillin-binding protein 2.
 
  
 0.737
Your Current Organism:
Sporosarcina newyorkensis
NCBI taxonomy Id: 759851
Other names: CCUG 59649, DSM 23544, LMG 26022, LMG:26022, S. newyorkensis, Sporosarcina newyorkensis Wolfgang et al. 2012, Sporosarcina sp. 3418, Sporosarcina sp. 4331, Sporosarcina sp. 4469, Sporosarcina sp. 4974, Sporosarcina sp. 4984, Sporosarcina sp. 5353, Sporosarcina sp. 57, Sporosarcina sp. 5868, Sporosarcina sp. 6062, Sporosarcina sp. R-31323, strain 6062
Server load: low (24%) [HD]