STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDSE_1069Glycine cleavage system H protein, mitochondrial Flags: Precursor. (110 aa)    
Predicted Functional Partners:
SDSE_1067
SIR2 family protein.
 
  
 0.972
lplA
Lipoate-protein ligase A.
 
 
 0.963
lipL
K01932; Catalyzes the amidotransfer (transamidation) of the octanoyl moiety from octanoyl-GcvH to the lipoyl domain of the E2 subunit of lipoate-dependent enzymes; Belongs to the octanoyltransferase LipL family.
 
 
 0.938
SDSE_1068
UPF0189 protein M6_Spy0919.
 
  
 0.937
yqiG
K00317 trimethylamine dehydrogenase.
 
     0.921
lpdA
Dihydrolipoyl dehydrogenase.
  
 0.882
luxA
Hypothetical protein; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
 
   
 0.723
fhs
K01938 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family.
  
  
 0.682
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
  
 0.668
lplB
K03800 lipoate-protein ligase A.
   
 0.649
Your Current Organism:
Streptococcus dysgalactiae
NCBI taxonomy Id: 759913
Other names: S. dysgalactiae subsp. equisimilis AC-2713, Streptococcus dysgalactiae subsp. equisimilis AC-2713, Streptococcus dysgalactiae subsp. equisimilis str. AC-2713, Streptococcus dysgalactiae subsp. equisimilis strain AC-2713
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