STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadDNicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (193 aa)    
Predicted Functional Partners:
cinA
Competence damaged protein, CinA; Belongs to the CinA family.
  
 
 0.956
ADK31173.1
Deacetylase.
   
 0.920
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
  
 
 0.920
ppnK
Inorganic polyphosphate ATP-dependent NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.920
nadE
NAD+synthetase.
  
 
 0.920
nadR
Nicotinamide-nucleotide adenylyltransferase.
     
 0.910
ushA
5-nucleotidase/2,3-cyclic phosphodiesterase and related esterase; Belongs to the 5'-nucleotidase family.
     
  0.900
ADK30122.1
Putative lipoprotein.
     
 0.785
ADK30394.1
Metal-dependent phosphohydrolase.
 
  
 0.729
ribD
Riboflavin biosynthesis protein, RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.670
Your Current Organism:
Brachyspira pilosicoli
NCBI taxonomy Id: 759914
Other names: B. pilosicoli 95/1000, Brachyspira pilosicoli 95/1000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.