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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
AEC01252.1COGs: COG2140 Thermophilic glucose-6-phosphate isomerase and related metalloenzyme; InterPro IPR010551; KEGG: art:Arth_1801 glucose-6-phosphate isomerase; PFAM: Glucose-6-phosphate isomerase, prokaryote; PRIAM: Glucose-6-phosphate isomerase; SPTR: Glucose-6-phosphate isomerase; IMG reference gene:2503956274; PFAM: Glucose-6-phosphate isomerase (GPI). (192 aa)    
Predicted Functional Partners:
AEC01251.1
Hypothetical protein; COGs: COG0169 Shikimate 5-dehydrogenase; KEGG: art:Arth_1802 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956273.
 
     0.916
AEC01510.1
Mannose-6-phosphate isomerase, class I; COGs: COG1482 Phosphomannose isomerase; InterPro IPR001250; KEGG: dol:Dole_2015 mannose-6-phosphate isomerase, class I; PFAM: Mannose-6-phosphate isomerase, type I; PRIAM: Mannose-6-phosphate isomerase; SPTR: Mannose-6-phosphate isomerase, class I; TIGRFAM: Mannose-6-phosphate isomerase, type I; IMG reference gene:2503956550; PFAM: Phosphomannose isomerase type I; TIGRFAM: mannose-6-phosphate isomerase, class I.
    
  0.905
AEC01336.1
Glucokinase; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: eat:EAT1b_0550 glucokinase, ROK family; PFAM: ROK; PRIAM: Glucokinase; SPTR: Glucokinase, ROK family; IMG reference gene:2503956358; PFAM: ROK family; TIGRFAM: ROK family protein (putative glucokinase).
    
  0.903
AEC02239.1
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; COGs: COG1109 Phosphomannomutase; InterPro IPR005844:IPR005845; KEGG: sta:STHERM_c11950 hypothetical protein; PFAM: Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; SPTR: Putative uncharacterized protein; IMG reference gene:2503957323; PFAM: Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III; Phosphoglucomutase/phosphomannomutase, C-terminal domain; Phosphoglucomutase/phosphomannom [...]
    
  0.903
AEC02821.1
Glucokinase; COGs: COG1940 Transcriptional regulator/sugar kinase; InterPro IPR000600; KEGG: tte:TTE0761 transcriptional regulator; PFAM: ROK; PRIAM: Glucokinase; SPTR: Putative uncharacterized protein; IMG reference gene:2503957936; PFAM: ROK family.
    
  0.903
AEC02170.1
Fructokinase; COGs: COG0524 Sugar kinase ribokinase family; InterPro IPR011611; KEGG: msv:Mesil_1102 PfkB domain protein; PFAM: Carbohydrate/purine kinase; PRIAM: Fructokinase; SPTR: PfkB domain protein; IMG reference gene:2503957250; PFAM: pfkB family carbohydrate kinase.
   
 
 0.902
pgi
COGs: COG0166 Glucose-6-phosphate isomerase; HAMAP: Phosphoglucose isomerase (PGI); InterPro IPR001672; KEGG: ssm:Spirs_3245 phosphoglucose isomerase (PGI); PFAM: Phosphoglucose isomerase (PGI); PRIAM: Glucose-6-phosphate isomerase; SPTR: Glucose-6-phosphate isomerase; IMG reference gene:2503958102; PFAM: Phosphoglucose isomerase; Belongs to the GPI family.
    
  0.901
AEC01363.1
COGs: COG3959 Transketolase N-terminal subunit; InterPro IPR005474; KEGG: ssm:Spirs_2992 transketolase domain protein; PFAM: Transketolase, N-terminal; PRIAM: Transketolase; SPTR: Transketolase domain protein; IMG reference gene:2503956385; PFAM: Transketolase, thiamine diphosphate binding domain.
     
  0.900
AEC01364.1
1-deoxy-D-xylulose-5-phosphate synthase; COGs: COG3958 Transketolase C-terminal subunit; InterPro IPR005475:IPR005476; KEGG: ssm:Spirs_2991 transketolase domain protein; PFAM: Transketolase-like, pyrimidine-binding domain; Transketolase, C-terminal; PRIAM: 1-deoxy-D-xylulose-5-phosphate synthase; SMART: Transketolase-like, pyrimidine-binding domain; SPTR: Transketolase domain protein; IMG reference gene:2503956386; PFAM: Transketolase, C-terminal domain; Transketolase, pyrimidine binding domain.
     
  0.900
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
     
  0.900
Your Current Organism:
Sphaerochaeta coccoides
NCBI taxonomy Id: 760011
Other names: S. coccoides DSM 17374, Sphaerochaeta coccoides DSM 17374, Sphaerochaeta coccoides str. DSM 17374, Sphaerochaeta coccoides strain DSM 17374, Spirochaeta coccoides DSM 17374, Spirochaeta coccoides SPN1, Spirochaeta sp. SPN1
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