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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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AEC01310.13-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR020842; KEGG: ssm:Spirs_3584 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SMART: Polyketide synthase/Fatty acid synthase, KR; SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2503956332; PFAM: short chain dehydrogenase. (247 aa)    
Predicted Functional Partners:
AEC01312.1
KEGG: ssm:Spirs_2366 hypothetical protein; SPTR: Transcriptional regulator; IMG reference gene:2503956334.
  
  
 0.787
AEC01308.1
Inosine guanosine and xanthosine phosphorylase family; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
    0.784
AEC01309.1
Protein of unknown function DUF985; COGs: COG3542 conserved hypothetical protein; InterPro IPR009327; KEGG: sco:SCO4051 hypothetical protein; PFAM: Protein of unknown function DUF985; SPTR: Putative uncharacterized protein; IMG reference gene:2503956331; PFAM: Cupin superfamily (DUF985).
       0.781
AEC01311.1
Metallophosphoesterase; COGs: COG2129 phosphoesterase related to the Icc protein; InterPro IPR004843; KEGG: sta:STHERM_c06590 Ser/Thr protein phosphatase family protein; PFAM: Metallo-dependent phosphatase; SPTR: Metallophosphoesterase; IMG reference gene:2503956333; PFAM: Calcineurin-like phosphoesterase.
       0.781
AEC02775.1
3-oxoacyl-(acyl-carrier-protein) reductase; COGs: COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase); InterPro IPR002198:IPR020842; KEGG: pac:PPA0372 3-ketoacyl-(acyl-carrier-protein) reductase; PFAM: Short-chain dehydrogenase/reductase SDR; PRIAM: 3-oxoacyl-[acyl-carrier-protein] reductase; SMART: Polyketide synthase/Fatty acid synthase, KR; SPTR: Short-chain dehydrogenase/reductase SDR; IMG reference gene:2503957887; PFAM: short chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.768
AEC01804.1
Short-chain dehydrogenase/reductase SDR; COGs: COG0300 Short-chain dehydrogenase of various substrate specificities; InterPro IPR002198; KEGG: cak:Caul_2944 short-chain dehydrogenase/reductase SDR; PFAM: Short-chain dehydrogenase/reductase SDR; SPTR: Oxidoreductase, short chain dehydrogenase/reductase family protein; IMG reference gene:2503956855; PFAM: short chain dehydrogenase.
 
 
 0.596
AEC02764.1
COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR014043:IPR020801; KEGG: sta:STHERM_c21550 hypothetical protein; PFAM: Acyl transferase; PRIAM: [Acyl-carrier-protein] S-malonyltransferase; SMART: Polyketide synthase, acyl transferase domain; SPTR: Putative uncharacterized protein; IMG reference gene:2503957876; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase.
 
 
 0.538
AEC01360.1
Ankyrin; InterPro IPR002110; KEGG: wpi:WPa_1379 ankyrin repeat domain protein; PFAM: Ankyrin repeat; SPTR: FOG: Ankyrin repeat; IMG reference gene:2503956382; PFAM: Ankyrin repeat.
   
 0.505
AEC03059.1
Peptidylprolyl isomerase; COGs: COG0652 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family; InterPro IPR002130:IPR001179; KEGG: dps:DP1645 peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, cyclophilin-type; Peptidyl-prolyl cis-trans isomerase, FKBP-type; PRIAM: Peptidylprolyl isomerase; SPTR: Probable peptidyl-prolyl cis-trans isomerase; IMG reference gene:2503958183; PFAM: FKBP-type peptidyl-prolyl cis-trans isomerase; Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD.
  
 
 0.505
AEC01297.1
Transcriptional regulator, AraC family; COGs: COG1609 Transcriptional regulators; InterPro IPR001761:IPR000005:IPR018060; KEGG: cag:Cagg_2054 two component transcriptional regulator, AraC family; PFAM: HTH transcriptional regulator, AraC; Periplasmic binding protein/LacI transcriptional regulator; SMART: Helix-turn-helix, AraC type, DNA binding domain; SPTR: Two component transcriptional regulator, AraC family; IMG reference gene:2503956319; PFAM: Bacterial regulatory helix-turn-helix proteins, AraC family; family.
  
 
 0.461
Your Current Organism:
Sphaerochaeta coccoides
NCBI taxonomy Id: 760011
Other names: S. coccoides DSM 17374, Sphaerochaeta coccoides DSM 17374, Sphaerochaeta coccoides str. DSM 17374, Sphaerochaeta coccoides strain DSM 17374, Spirochaeta coccoides DSM 17374, Spirochaeta coccoides SPN1, Spirochaeta sp. SPN1
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