Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEC01816.1InterPro IPR007452; KEGG: ssm:Spirs_2021 protein of unknown function DUF490; PFAM: Protein of unknown function DUF490; SPTR: Putative uncharacterized protein; IMG reference gene:2503956867; PFAM: Family of unknown function (DUF490). (1650 aa)    
Predicted Functional Partners:
AEC01817.1
COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184:IPR016474; KEGG: ssm:Spirs_2022 outer membrane protein assembly complex, YaeT protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Putative surface antigen; TIGRFAM: Outer membrane assembly protein, YaeT; IMG reference gene:2503956868; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.
     
 0.781
mutS
DNA mismatch repair protein mutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
       0.584
AEC01819.1
Hypothetical protein; COGs: COG1040 amidophosphoribosyltransferase; KEGG: ele:Elen_1211 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503956870.
       0.547
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
       0.533
Your Current Organism:
Sphaerochaeta coccoides
NCBI taxonomy Id: 760011
Other names: S. coccoides DSM 17374, Sphaerochaeta coccoides DSM 17374, Sphaerochaeta coccoides str. DSM 17374, Sphaerochaeta coccoides strain DSM 17374, Spirochaeta coccoides DSM 17374, Spirochaeta coccoides SPN1, Spirochaeta sp. SPN1
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