Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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AEC02023.1Oligopeptidase F; COGs: COG1164 Oligoendopeptidase F; InterPro IPR013647:IPR001567:IPR004438; KEGG: ssm:Spirs_1288 oligoendopeptidase F; PFAM: Peptidase M3A/M3B, thimet/oligopeptidase F; Peptidase M3B, oligopeptidase F, N-terminal; SPTR: Oligoendopeptidase F; TIGRFAM: Peptidase M3B, oligoendopeptidase F; IMG reference gene:2503957098; PFAM: Oligopeptidase F; Peptidase family M3; TIGRFAM: oligoendopeptidase F. (600 aa)    
Predicted Functional Partners:
AEC02022.1
Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.807
AEC02021.1
KEGG: ssm:Spirs_1290 hypothetical protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957096.
       0.788
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
     
 0.529
AEC02020.1
Phosphoesterase RecJ domain protein; COGs: COG0618 Exopolyphosphatase-related protein; InterPro IPR001667:IPR003156; KEGG: tde:TDE1479 DHH superfamily protein, subfamily 1; PFAM: Phosphoesterase, RecJ-like; Phosphoesterase, DHHA1; SPTR: DHH superfamily protein, subfamily 1; IMG reference gene:2503957095; PFAM: DHH family; DHHA1 domain.
       0.510
clpP
ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
     
 0.508
AEC02507.1
COGs: COG0015 Adenylosuccinate lyase; InterPro IPR004769:IPR022761:IPR019468; KEGG: cpy:Cphy_3043 adenylosuccinate lyase; PFAM: Lyase 1, N-terminal; Adenylosuccinate lyase C-terminal metazoa/fungi; SPTR: Putative uncharacterized protein; TIGRFAM: Adenylosuccinate lyase; IMG reference gene:2503957609; PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
    0.406
Your Current Organism:
Sphaerochaeta coccoides
NCBI taxonomy Id: 760011
Other names: S. coccoides DSM 17374, Sphaerochaeta coccoides DSM 17374, Sphaerochaeta coccoides str. DSM 17374, Sphaerochaeta coccoides strain DSM 17374, Spirochaeta coccoides DSM 17374, Spirochaeta coccoides SPN1, Spirochaeta sp. SPN1
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