Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
AEC02230.1BioY protein; COGs: COG1268 conserved hypothetical protein; InterPro IPR003784; KEGG: sta:STHERM_c14470 biotin synthesis protein BioY; PFAM: BioY protein; SPTR: Biotin synthesis protein BioY; IMG reference gene:2503957313; PFAM: BioY family. (192 aa)    
Predicted Functional Partners:
AEC02334.1
Fe(3+)-transporting ATPase; COGs: COG1122 ABC-type cobalt transport system ATPase component; InterPro IPR003439:IPR003593; KEGG: sfu:Sfum_1750 cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter-like; PRIAM: Fe(3+)-transporting ATPase; SMART: ATPase, AAA+ type, core; SPTR: Cobalt ABC transporter, ATPase subunit; IMG reference gene:2503957421; PFAM: ABC transporter.
 
 
 0.980
AEC02335.1
COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: dal:Dalk_0379 cobalt transport protein; PFAM: Cobalt transport protein; SPTR: Cobalt transport protein; IMG reference gene:2503957422; PFAM: Cobalt transport protein.
 
 0.936
AEC02532.1
COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: sti:Sthe_3088 cobalt transport protein; PFAM: Cobalt transport protein; SPTR: Cobalt transport protein; IMG reference gene:2503957638; PFAM: Cobalt transport protein.
  
 0.919
AEC02598.1
COGs: COG0619 ABC-type cobalt transport system permease component CbiQ and related transporter; InterPro IPR003339; KEGG: ssm:Spirs_3591 cobalt transport protein; PFAM: Cobalt transport protein; SPTR: Putative uncharacterized protein; IMG reference gene:2503957706; PFAM: Cobalt transport protein.
  
 0.919
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.886
AEC02231.1
COGs: COG1045 Serine acetyltransferase; InterPro IPR001451; KEGG: ssm:Spirs_1684 serine O-acetyltransferase; PFAM: Bacterial transferase hexapeptide repeat; PRIAM: Serine O-acetyltransferase; SPTR: Putative uncharacterized protein; IMG reference gene:2503957314; TIGRFAM: serine O-acetyltransferase.
       0.646
AEC02766.1
Biotin carboxylase; COGs: COG4770 Acetyl/propionyl-CoA carboxylase alpha subunit; InterPro IPR005481:IPR005479:IPR005482; KEGG: sta:STHERM_c08570 pyruvate carboxylase subunit A; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Biotin carboxylase, C-terminal; PRIAM: Biotin carboxylase; SMART: Biotin carboxylase, C-terminal; SPTR: Pyruvate carboxylase subunit A; IMG reference gene:2503957878; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; Biotin carboxylase C-terminal domain; Carbamoyl-phosphate sy [...]
 
     0.455
argS
COGs: COG0018 Arginyl-tRNA synthetase; HAMAP: Arginyl-tRNA synthetase, class Ic; InterPro IPR001278:IPR005148:IPR015945:IPR008909; KEGG: ssm:Spirs_1801 arginyl-tRNA synthetase; PFAM: Arginyl-tRNA synthetase, class Ic, core; Arginyl tRNA synthetase, class Ic, N-terminal; DALR anticodon binding; PRIAM: Arginine--tRNA ligase; SMART: DALR anticodon binding; SPTR: Putative uncharacterized protein; TIGRFAM: Arginyl-tRNA synthetase, class Ic; IMG reference gene:2503957311; PFAM: DALR anticodon binding domain; Arginyl tRNA synthetase N terminal domain; tRNA synthetases class I (R); TIGRFAM: ar [...]
       0.406
Your Current Organism:
Sphaerochaeta coccoides
NCBI taxonomy Id: 760011
Other names: S. coccoides DSM 17374, Sphaerochaeta coccoides DSM 17374, Sphaerochaeta coccoides str. DSM 17374, Sphaerochaeta coccoides strain DSM 17374, Spirochaeta coccoides DSM 17374, Spirochaeta coccoides SPN1, Spirochaeta sp. SPN1
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