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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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AEC02249.1COGs: COG0284 Orotidine-5'-phosphate decarboxylase; InterPro IPR001754:IPR011995; KEGG: ssm:Spirs_1435 orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase domain; PRIAM: Orotidine-5'-phosphate decarboxylase; SMART: Orotidine 5'-phosphate decarboxylase domain; SPTR: Orotidine 5'-phosphate decarboxylase; TIGRFAM: Orotidine 5'-phosphate decarboxylase, type 2; IMG reference gene:2503957333; PFAM: Orotidine 5'-phosphate decarboxylase / HUMPS family; TIGRFAM: orotidine 5'-phosphate decarboxylase, subfamily 2. (312 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.998
AEC02251.1
COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006132:IPR006131:IPR002082; KEGG: tde:TDE0129 bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; PRIAM: Aspartate carbamoyltransferase; SPTR: Protein pyrBI; TIGRFAM: Aspartate carbamoyltransferase, eukaryotic; IMG reference gene:2503957335; PFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspa [...]
 
  
 0.998
AEC02248.1
COGs: COG0167 Dihydroorotate dehydrogenase; InterPro IPR012135:IPR008333:IPR001433:IPR005720; KEGG: tde:TDE0982 dihydroorotate dehydrogenase/oxidoreductase, FAD-binding; PFAM: Dihydroorotate dehydrogenase, class 1/ 2; Oxidoreductase, FAD-binding domain; Oxidoreductase FAD/NAD(P)-binding; SPTR: Dihydroorotate dehydrogenase/oxidoreductase, FAD-binding; TIGRFAM: Dihydroorotate dehydrogenase, class 1; IMG reference gene:2503957332; PFAM: Dihydroorotate dehydrogenase; TIGRFAM: dihydroorotate dehydrogenase (subfamily 1) family protein.
  
  
 0.997
AEC02247.1
Dihydroorotase, putative; COGs: COG0044 Dihydroorotase and related cyclic amidohydrolase; KEGG: tde:TDE2107 dihydroorotase, putative; SPTR: Dihydroorotase, putative; IMG reference gene:2503957331.
 
  
 0.986
AEC01954.1
COGs: COG0035 Uracil phosphoribosyltransferase; KEGG: ssm:Spirs_1527 phosphoribosyl transferase domain-containing protein; SPTR: Phosphoribosyl transferase domain protein; IMG reference gene:2503957018.
 
 
 0.939
AEC02929.1
COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR006275:IPR005481:IPR005479:IPR005480:IPR 011607; KEGG: sta:STHERM_c07390 carbamoyl-phosphate synthase large chain; PFAM: Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Methylglyoxal synthase-like domain; PRIAM: Carbamoyl-phosphate synthase (ammonia); SMART: Methylglyoxal synthase-like domain; SPTR: Carbamoyl-phosphate synthase large chain; TIGRFAM: Carbamoyl-phosphate [...]
 
  
 0.936
carA
COGs: COG0505 Carbamoylphosphate synthase small subunit; InterPro IPR006274:IPR002474:IPR000991; KEGG: ssm:Spirs_3538 carbamoyl-phosphate synthase, small subunit; PFAM: Glutamine amidotransferase class-I, C-terminal; Carbamoyl-phosphate synthase, small subunit, N-terminal; PRIAM: Carbamoyl-phosphate synthase (glutamine-hydrolyzing); SPTR: Carbamoyl-phosphate synthase small chain; TIGRFAM: Carbamoyl-phosphate synthase, small subunit; IMG reference gene:2503958048; PFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosph [...]
 
  
 0.934
AEC02277.1
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.923
surE
Multifunctional protein surE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.917
AEC02439.1
AAA ATPase; COGs: COG0572 Uridine kinase; InterPro IPR003593; KEGG: ssm:Spirs_3160 AAA ATPase; SMART: ATPase, AAA+ type, core; SPTR: Uridine kinase; IMG reference gene:2503957537; PFAM: Phosphoribulokinase / Uridine kinase family.
  
 
 0.913
Your Current Organism:
Sphaerochaeta coccoides
NCBI taxonomy Id: 760011
Other names: S. coccoides DSM 17374, Sphaerochaeta coccoides DSM 17374, Sphaerochaeta coccoides str. DSM 17374, Sphaerochaeta coccoides strain DSM 17374, Spirochaeta coccoides DSM 17374, Spirochaeta coccoides SPN1, Spirochaeta sp. SPN1
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