Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (579 aa)    
Predicted Functional Partners:
AEC02446.1
CinA domain protein; COGs: COG1546 Uncharacterized protein (competence- and mitomycin-induced); InterPro IPR001453:IPR008136; KEGG: ssm:Spirs_3180 competence/damage-inducible protein CinA; PFAM: CinA, C-terminal; Molybdopterin binding; SMART: Molybdopterin binding; SPTR: CinA-like protein; TIGRFAM: CinA, C-terminal; IMG reference gene:2503957544; PFAM: Probable molybdopterin binding domain; Competence-damaged protein; TIGRFAM: competence/damage-inducible protein CinA N-terminal domain; competence/damage-inducible protein CinA C-terminal domain; molybdenum cofactor synthesis domain.
       0.812
AEC01817.1
COGs: COG4775 Outer membrane protein/protective antigen OMA87; InterPro IPR010827:IPR000184:IPR016474; KEGG: ssm:Spirs_2022 outer membrane protein assembly complex, YaeT protein; PFAM: Bacterial surface antigen (D15); Surface antigen variable number; SPTR: Putative surface antigen; TIGRFAM: Outer membrane assembly protein, YaeT; IMG reference gene:2503956868; PFAM: Surface antigen variable number repeat; Surface antigen; TIGRFAM: outer membrane protein assembly complex, YaeT protein.
 
   
 0.784
AEC02448.1
Histone family protein DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
 
     0.753
AEC02793.1
COGs: COG1466 DNA polymerase III delta subunit; InterPro IPR010372; KEGG: ssm:Spirs_4056 DNA polymerase III, delta subunit; PFAM: DNA polymerase III, delta; SPTR: Putative uncharacterized protein; IMG reference gene:2503957905; PFAM: DNA polymerase III, delta subunit; TIGRFAM: DNA polymerase III, delta subunit.
 
    0.681
AEC01537.1
InterPro IPR000297; KEGG: ssm:Spirs_1830 PpiC-type peptidyl-prolyl cis-trans isomerase; PFAM: Peptidyl-prolyl cis-trans isomerase, PpiC-type; SPTR: Putative uncharacterized protein; IMG reference gene:2503956579; PFAM: PPIC-type PPIASE domain.
 
   
 0.674
AEC01829.1
Permease YjgP/YjgQ family protein; COGs: COG0795 permease; InterPro IPR005495; KEGG: sta:STHERM_c11120 hypothetical protein; PFAM: Permease YjgP/YjgQ, predicted; SPTR: Putative uncharacterized protein; IMG reference gene:2503956880; PFAM: Predicted permease YjgP/YjgQ family.
 
     0.667
yidC
Membrane protein oxaA; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
   
 0.658
AEC01845.1
Protein of unknown function DUF164; COGs: COG1579 Zn-ribbon protein possibly nucleic acid-binding; InterPro IPR003743; KEGG: ssm:Spirs_2077 protein of unknown function DUF164; PFAM: Protein of unknown function DUF164; SPTR: Putative nucleic acid-binding Zn-ribbon protein; IMG reference gene:2503956897; PFAM: Putative zinc ribbon domain.
  
     0.645
AEC02399.1
InterPro IPR000182; KEGG: ssm:Spirs_3745 GCN5-related N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase (GNAT) domain; SPTR: Putative uncharacterized protein; IMG reference gene:2503957495; PFAM: Acetyltransferase (GNAT) family; Uncharacterised protein family (UPF0158).
 
   
 0.626
AEC02803.1
KEGG: ssm:Spirs_4125 hypothetical protein; SPTR: Putative cytoplasmic protein; IMG reference gene:2503957915.
  
     0.622
Your Current Organism:
Sphaerochaeta coccoides
NCBI taxonomy Id: 760011
Other names: S. coccoides DSM 17374, Sphaerochaeta coccoides DSM 17374, Sphaerochaeta coccoides str. DSM 17374, Sphaerochaeta coccoides strain DSM 17374, Spirochaeta coccoides DSM 17374, Spirochaeta coccoides SPN1, Spirochaeta sp. SPN1
Server load: medium (54%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.