| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AEA33666.1 | AEA34035.1 | Hipma_0696 | Hipma_1069 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.928 |
| AEA33666.1 | birA | Hipma_0696 | Hipma_1047 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.557 |
| AEA33666.1 | panB | Hipma_0696 | Hipma_1074 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.912 |
| AEA33666.1 | panC | Hipma_0696 | Hipma_1073 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.912 |
| AEA34034.1 | AEA34035.1 | Hipma_1068 | Hipma_1069 | COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: ddf:DEFDS_1460 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.640 |
| AEA34034.1 | AEA34036.1 | Hipma_1068 | Hipma_1070 | COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: ddf:DEFDS_1460 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain. | KEGG: pat:Patl_1120 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.636 |
| AEA34034.1 | AEA34037.1 | Hipma_1068 | Hipma_1071 | COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: ddf:DEFDS_1460 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain. | KEGG: pth:PTH_1495 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1446). | 0.636 |
| AEA34034.1 | panB | Hipma_1068 | Hipma_1074 | COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: ddf:DEFDS_1460 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.577 |
| AEA34034.1 | panC | Hipma_1068 | Hipma_1073 | COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: ddf:DEFDS_1460 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.577 |
| AEA34034.1 | panD | Hipma_1068 | Hipma_1072 | COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: ddf:DEFDS_1460 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.666 |
| AEA34035.1 | AEA33666.1 | Hipma_1069 | Hipma_0696 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.928 |
| AEA34035.1 | AEA34034.1 | Hipma_1069 | Hipma_1068 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: ddf:DEFDS_1460 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain. | 0.640 |
| AEA34035.1 | AEA34036.1 | Hipma_1069 | Hipma_1070 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | KEGG: pat:Patl_1120 hypothetical protein; SPTR: Putative uncharacterized protein. | 0.818 |
| AEA34035.1 | AEA34037.1 | Hipma_1069 | Hipma_1071 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | KEGG: pth:PTH_1495 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1446). | 0.818 |
| AEA34035.1 | AEA34041.1 | Hipma_1069 | Hipma_1075 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: tte:TTE2369 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hyd [...] | 0.481 |
| AEA34035.1 | AEA34042.1 | Hipma_1069 | Hipma_1076 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR019881; IPR004839; KEGG: aae:aq_273 LL-diaminopimelate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: LL-diaminopimelate aminotransferase; SPTR: LL-diaminopimelate aminotransferase; TIGRFAM: LL-diaminopimelate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: LL-diaminopimelate aminotransferase. | 0.517 |
| AEA34035.1 | birA | Hipma_1069 | Hipma_1047 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.577 |
| AEA34035.1 | panB | Hipma_1069 | Hipma_1074 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.973 |
| AEA34035.1 | panC | Hipma_1069 | Hipma_1073 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.975 |
| AEA34035.1 | panD | Hipma_1069 | Hipma_1072 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.802 |