STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEA34035.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (312 aa)    
Predicted Functional Partners:
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
 
  
 0.975
panB
3-methyl-2-oxobutanoatehydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.973
AEA33666.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
  
 
0.928
AEA34036.1
KEGG: pat:Patl_1120 hypothetical protein; SPTR: Putative uncharacterized protein.
  
    0.818
AEA34037.1
KEGG: pth:PTH_1495 hypothetical protein; SPTR: Putative uncharacterized protein; PFAM: Protein of unknown function (DUF1446).
  
    0.818
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
 0.802
AEA34034.1
COGs: COG0810 Periplasmic protein TonB links inner and outer membranes; InterPro IPR006260; KEGG: ddf:DEFDS_1460 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: TonB, C-terminal; PFAM: Gram-negative bacterial tonB protein; TIGRFAM: TonB family C-terminal domain.
  
    0.640
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
 
   
 0.577
AEA34042.1
COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR019881; IPR004839; KEGG: aae:aq_273 LL-diaminopimelate aminotransferase; PFAM: Aminotransferase, class I/classII; PRIAM: LL-diaminopimelate aminotransferase; SPTR: LL-diaminopimelate aminotransferase; TIGRFAM: LL-diaminopimelate aminotransferase; PFAM: Aminotransferase class I and II; TIGRFAM: LL-diaminopimelate aminotransferase.
 
    0.517
AEA34041.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; COGs: COG0801 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; InterPro IPR000550; KEGG: tte:TTE2369 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; PFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PRIAM:2-amino-4-hydroxy-6-hydroxymethyldihydropteri dinediphosphokinase; SPTR: 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase; TIGRFAM: 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK; PFAM: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK); TIGRFAM: 2-amino-4-hydroxy-6-hyd [...]
     
 0.481
Your Current Organism:
Hippea maritima
NCBI taxonomy Id: 760142
Other names: H. maritima DSM 10411, Hippea maritima DSM 10411, Hippea maritima MS2, Hippea maritima MS[subscript]2, Hippea maritima str. DSM 10411, Hippea maritima strain DSM 10411
Server load: low (16%) [HD]