STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEA34393.1Protein of unknown function UPF0047; COGs: COG0432 conserved hypothetical protein; InterPro IPR001602; KEGG: ddf:DEFDS_1845 hypothetical protein; PFAM: Uncharacterised protein family UPF0047; SPTR: Putative uncharacterized protein; TIGRFAM: Uncharacterised protein family UPF0047; PFAM: Uncharacterised protein family UPF0047; TIGRFAM: secondary thiamine-phosphate synthase enzyme. (139 aa)    
Predicted Functional Partners:
AEA34390.1
Drug resistance transporter, EmrB/QacA subfamily; COGs: COG2814 Arabinose efflux permease; InterPro IPR011701; IPR004638; KEGG: sfu:Sfum_3317 EmrB/QacA family drug resistance transporter; PFAM: Major facilitator superfamily MFS-1; SPTR: Drug resistance transporter, EmrB/QacA subfamily; TIGRFAM: Drug resistance transporter EmrB/QacA subfamily; PFAM: Major Facilitator Superfamily; TIGRFAM: drug resistance transporter, EmrB/QacA subfamily.
  
    0.773
AEA34391.1
Secretion protein HlyD family protein; COGs: COG1566 Multidrug resistance efflux pump; InterPro IPR006143; KEGG: gur:Gura_3091 secretion protein HlyD family protein; PFAM: Secretion protein HlyD; SPTR: Secretion protein HlyD family protein; PFAM: HlyD family secretion protein.
       0.773
AEA34392.1
Transcriptional regulator, MarR family; COGs: COG1846 Transcriptional regulators; InterPro IPR000835; KEGG: mma:MM_1863 MarR family transcriptional regulator; PFAM: HTH transcriptional regulator, MarR; SMART: HTH transcriptional regulator, MarR; SPTR: Putative uncharacterized protein; PFAM: MarR family.
       0.773
AEA34394.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
       0.635
AEA34395.1
COGs: COG0307 Riboflavin synthase alpha chain; InterPro IPR001783; KEGG: tal:Thal_0638 riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; PRIAM: Riboflavin synthase; SPTR: Riboflavin synthase, alpha subunit; TIGRFAM: Lumazine-binding protein; PFAM: Lumazine binding domain; TIGRFAM: riboflavin synthase, alpha subunit.
  
    0.556
AEA34389.1
KEGG: saf:SULAZ_0883 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.513
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
       0.440
AEA34387.1
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR003660; IPR003661; IPR003594; KEGG: sul:SYO3AOP1_0141 integral membrane sensor signal transduction histidine kinase; PFAM: Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; ATPase-like, ATP-binding domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; SPTR: Integral membrane sensor signal transduction histidine kinase; PFAM: Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Ki [...]
       0.424
AEA34388.1
Two component transcriptional regulator, winged helix family; COGs: COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; InterPro IPR001789; IPR001867; KEGG: saf:SULAZ_0884 two-component response regulator; PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SPTR: Two-component response regulator; PFAM: Response regulator receiver domain; Transcriptional [...]
       0.424
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
    0.416
Your Current Organism:
Hippea maritima
NCBI taxonomy Id: 760142
Other names: H. maritima DSM 10411, Hippea maritima DSM 10411, Hippea maritima MS2, Hippea maritima MS[subscript]2, Hippea maritima str. DSM 10411, Hippea maritima strain DSM 10411
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